According to the Natchez Democrat:
An abandoned service station and former hotel building were destroyed in the fire, the dispatcher said. The building was once reportedly home to the African-American entertainers of the Rabbit Foot Minstrels, which have a Mississippi Blues Trail marker at the building’s location.
A neighboring building, formerly a Masonic lodge, also burned as well as a brick storage structure.
These were on the south end of downtown, where Market Street intersects with Carrol Street. Both buildings were contributing to the National Register historic district, but both had been vacant for some time. Presumably neither had electricity turned on, and the two buildings were separated by a wide vacant lot.